Mechanical and Pharmacological Revascularization Strategies for Prevention of Microvascular Dysfunction in ST-Segment Elevation Myocardial Infarction: Analysis from Index of Microcirculatory Resistance Registry Data

Table 5

Results of multiple linear regression analysis for clinical, echocardiographic, and angiographic factors correlated with IMR value.

Parameter	Univariable analysis			Multiple analysis
	β	SE	value	β	SE	value
Age	0.35	0.14	0.017	0.23	0.16	0.538
Male	−3.53	5.13	0.493
Killip class	13.65	3.10	<0.001	8.18	2.89	0.006
SHT	5.40	1.54	<0.001	3.88	1.33	0.004
LVEF	−0.67	0.23	0.005
E/e’	0.78	0.58	0.183
WMSI	17.12	5.49	0.002
LV mass index	0.18	0.07	0.018
CK-MB peak	2.64	1.55	0.093
Troponin-I peak	3.91	1.44	0.008	2.52	1.22	0.042
NT-proBNP	5.08	1.43	<0.001
Multivessel disease	11.47	3.44	0.001	9.09	2.93	0.003
Initial TIMI 0-1	5.92	3.62	0.105
Final TIMI 3	−5.40	6.99	0.442
Final TMPG 3	−8.10	3.76	0.034	−5.00	3.17	0.119
Distal embolization	14.17	4.44	0.002	8.38	3.88	0.034

β, Unstandardized coefficients; CK-MB, creatine kinase muscle/brain; LV, left ventricle; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; SE, standard error; SHT, symptom onset to hospital time; TIMI, thrombolysis in myocardial infarction; TMPG, thrombolysis in myocardial infarction myocardial perfusion grade; WMSI, wall motion score index. Data were expressed as quartile (1^st∼4^th).