Clinical Study

Combined Therapy of Catheter Ablation and Left Atrial Appendage Closure for Patients with Atrial Fibrillation: A Case-Control Study

Table 3

Catheter ablation and arrhythmia follow-up.

Combined (n = 76)CA-only (n = 76)

Mapping system
  CARTO33 (43.4)37 (48.7)0.515
  EnSite43 (56.6)39 (51.3)0.515
PVI only39 (51.3)41 (53.9)0.745
PVI plus linear/CFAE ablation37 (48.7)35 (46.1)0.745
Cardioversion36 (47.4)32 (42.1)0.514
Procedure time (min)129 ± 24.5133.1 ± 26.40.388
Fluoroscopy time (min)5.4 ± 2.45.9 ± 2.60.336
Complications3 (3.9)2 (2.6)0.650
 Pericardial effusion1 (1.3)1 (1.3)1.000
 Stroke0 (0.0)0 (0.0)
 Major bleeding events0 (0.0)0 (0.0)
 Death0 (0.0)0 (0.0)
 Complications of vascular access2 (2.6)1 (1.3)0.561
Average follow-up (months)24.0 ± 5.223.7 ± 4.90.717
AF-free follow-up
 Overall51 (67.1)53 (69.7)0.727
 Paroxysmal AF26 (70.3)29 (76.3)0.554
 Persistent AF25 (64.1)24 (63.2)0.931
Redo ablation12 (15.8)9 (11.8)0.481
Follow-up events3 (3.9)4 (5.3)0.699
 Ischemic stroke events1 (1.3)1 (1.3)1.000
 Bleeding events2 (2.6)3 (3.9)0.650

The procedure and fluoroscopy time were calculated from femoral venous puncture to the end of the ablation. Values are mean ± SD or n (%) as appropriate. AF, atrial fibrillation; CA, catheter ablation; CFAE, complex fragmented atrial electrogram; PVI, pulmonary vein isolation.