Combined Catheter Ablation and Left Atrial Appendage Closure in Atrial Fibrillation Patients with and without Prior Stroke
Table 1
Baseline characteristics of the study population.
Stroke group N = 81
Control group N = 215
value
Female
36 (44.4)
107 (49.8)
0.414
Age (years)
69.6 ± 8.2
68.9 ± 7.9
0.476
BMI (kg/m2)
24.5 ± 3.1
24.8 ± 3.4
0.492
Paroxysmal AF
40 (49.4)
97 (45.1)
0.512
Persistent AF
41 (50.6)
118 (54.9)
0.512
Coronary artery disease
15 (18.5)
49 (22.8)
0.426
Heart failure
17 (21.0)
58 (27.0)
0.291
Hypertension
64 (79.0)
175 (81.4)
0.643
Diabetes mellitus
18 (22.2)
65 (30.2)
0.171
Previous stroke
81 (100.0)
0 (0.0)
<0.001
Left atrial diameter (mm)
43.1 ± 5.1
42.5 ± 5.7
0.353
LVEF (%)
62.8 ± 6.5
63.6 ± 6.3
0.359
CHA2DS2-VASc score
4.9 ± 1.2
3.2 ± 1.0
<0.001
HAS-BLED score
3.5 ± 1.1
3.0 ± 1.0
<0.001
Indications for LAAC
<0.001
High bleeding risk
40 (49.4)
124 (57.7)
History of stroke under OAC
21 (25.9)
0 (0.0)
Intolerance to chronic OAC
7 (8.6)
22 (10.2)
Patient preference
13 (16.0)
69 (32.1)
Values are mean ± SD or n (%) as appropriate. AF, atrial fibrillation; BMI, body mass index; LAAC, left atrial appendage closure; LVEF, left ventricular ejection fraction; OAC, oral anticoagulation.