Research Article

Combined Catheter Ablation and Left Atrial Appendage Closure in Atrial Fibrillation Patients with and without Prior Stroke

Table 1

Baseline characteristics of the study population.

Stroke group
N = 81
Control group
N = 215
value

Female36 (44.4)107 (49.8)0.414
Age (years)69.6 ± 8.268.9 ± 7.90.476
BMI (kg/m2)24.5 ± 3.124.8 ± 3.40.492
Paroxysmal AF40 (49.4)97 (45.1)0.512
Persistent AF41 (50.6)118 (54.9)0.512
Coronary artery disease15 (18.5)49 (22.8)0.426
Heart failure17 (21.0)58 (27.0)0.291
Hypertension64 (79.0)175 (81.4)0.643
Diabetes mellitus18 (22.2)65 (30.2)0.171
Previous stroke81 (100.0)0 (0.0)<0.001
Left atrial diameter (mm)43.1 ± 5.142.5 ± 5.70.353
LVEF (%)62.8 ± 6.563.6 ± 6.30.359
CHA2DS2-VASc score4.9 ± 1.23.2 ± 1.0<0.001
HAS-BLED score3.5 ± 1.13.0 ± 1.0<0.001
Indications for LAAC<0.001
 High bleeding risk40 (49.4)124 (57.7)
 History of stroke under OAC21 (25.9)0 (0.0)
 Intolerance to chronic OAC7 (8.6)22 (10.2)
 Patient preference13 (16.0)69 (32.1)

Values are mean ± SD or n (%) as appropriate. AF, atrial fibrillation; BMI, body mass index; LAAC, left atrial appendage closure; LVEF, left ventricular ejection fraction; OAC, oral anticoagulation.