Drug-Coated Balloon-Only Angioplasty Outcomes in Diabetic and Nondiabetic Patients with De Novo Small Coronary Vessels Disease

Table 1

Patients’ baseline characteristics.

	Overall population (n = 1198)	Nondiabetic (n = 768)	Diabetic (n = 430)	value
Demographics
Sex
Male	831 (69.3%)	544 (70.8%)	287 (66.7%)	0.141
Female	367 (30.7%)	224 (29.1%)	143 (33.2%)	0.141
Age	60 ± 10.7	59 ± 10.9	60 ± 10.5	0.003
History and risk factor
Family history of CAD	223 (18.6%)	140 (18.2%)	83 (19.3%)	0.643
Current smoker	380 (31.7%)	245 (31.9%)	135 (31.3%)	0.857
Hyperlipidemia	340 (28.3%)	187 (24.3%)	153 (35.5%)	0.001
History of MI	117 (9.7%)	72 (9.3%)	45 (10.4%)	0.542
History of PCI	191 (15.9%)	105 (13.6%)	86 (20%)	0.004
History of CABG	19 (1.5%)	9 (1.1%)	10 (2.3%)	0.125
Laboratory tests
Hemoglobin (g/L)	135 ± 62.4	137 ± 77.4	131 ± 15.2	0.133
Hematocrit (%)	0.80 ± 4	0.94 ± 4.7	0.56 ± 2.4	0.141
Blood glucose (mmol/L)	173 ± 122	145 ± 91.	229 ± 146	0.001
HbA1C (%)	6 ± 3.4	5 ± 0.35	8 ± 5.06	0.001
Urea (mmol/dL)	5 ± 2.9	5 ± 1.8	6 ± 4.2	0.003
Creatinine (μmol/L)	75 ± 38.1	75 ± 34.9	75 ± 43	0.960
eGRF	90 ± 17	90 ± 15.9	89 ± 18.7	0.479
LDL (mmol/dL)	4 ± 64.8	5 ± 82.5	2 ± 0.7	0.424
HDL (mmol/dL)	2 ± 31.7	2 ± 40.3	0.9 ± 0.2	0.405
Albumin (g/L)	10 ± 13.5	10 ± 13.6	10 ± 13.4	0.831
Total cholesterol (mmol/dL)	3 ± 2.5	3 ± 0.9	3 ± 3.9	0.309
Triglyceride (mmol/dL)	1 ± 0.9	1 ± 0.9	1 ± 1.07	0.001
NT-proBNP (pg/ml)	624 ± 1049.2	568 ± 898.5	720 ± 1266.6	0.079
cTnT (ng/L)	11 ± 18.2	11 ± 18.2	12 ± 18.6	0.560
cTnI (ng/L)	1.68 ± 3.8	1 ± 3.5	1 ± 4.3	0.506
Clinical presentation
Hypertension	623 (52.3%)	363 (47.2%)	260 (60.4%)	0.001
LVEF (%)	24 ± 16.6	24 ± 16.7	25 ± 16	0.622
Acute coronary syndrome	802 (66.9%)	515 (67%)	287 (66.7%)	0.912
Renal failure	57 (4.7%)	25 (3.2%)	32 (7.4%)	0.001
Insulin therapy	72 (6%)	0 (0%)	72 (16.7%)	0.001

Statistically significant. CABG: coronary artery bypass graft; CAD: coronary artery disease; CRP: C-reactive protein; MI: myocardial infarction; cTnI: cardiac troponin I; cTnT: cardiac troponin T; eGFR: estimated glomerular filtration rate; HbA1C: glycosylated hemoglobin; HDL: high-density lipoprotein; LDL: low-density lipoprotein; NT-proBNP: N-terminal prohormone brain natriuretic peptide; PCI: percutaneous coronary intervention.