Simplified Assessment of the Index of Microvascular Resistance
Table 2
Invasive physiologic measurements with adenosine and papaverine.
Adenosine
Papaverine
value
N = 29
N = 29
IMR, mean ± SD
20.1 ± 8.60
17.7 ± 7.26
0.25
IMR corrected, mean ± SD
19.7 ± 8.51
17.5 ± 7.25
0.28
Tmn during rest, sec, mean ± SD
0.91 ± 0.40
0.92 ± 0.38
0.98
Tmn during hyperemia, sec, mean ± SD
0.29 ± 0.12
0.26 ± 0.11
0.33
Pd, mmHg, mean ± SD
70.7 ± 15.2
69.5 ± 12.5
0.75
Peak temperature, degree, median (IQR)
−4.33 (−5.89, −2.84)
−4.47 (−6.01, −3.75)
0.23
TRT, sec, median (IQR)
0.32 (0.26, 0.48)
0.28 (0.20, 0.36)
0.26
Derivative, degree/sec, median (IQR)
9.95 (5.19, 21.5)
17.3 (8.92, 24.3)
0.16
CFR, mean ± SD
3.15 ± 1.23
3.96 ± 1.58
0.03
FFR, mean ± SD
0.90 ± 0.08
0.92 ± 0.07
0.52
FFR, median (IQR)
0.91 (0.86, 0.97)
0.91 (0.87, 0.98)
0.61
IMR, index of microvascular resistance; IMR corrected, IMR corrected from influence of collateral supply; Tmn, mean transit time; Pd, distal pressure in a coronary; TRT, temperature recovery time; CFR, coronary flow reserve; FFR, fractional flow reserve.