Research Article

Simplified Assessment of the Index of Microvascular Resistance

Table 2

Invasive physiologic measurements with adenosine and papaverine.

AdenosinePapaverine value
N = 29N = 29

IMR, mean ± SD20.1 ± 8.6017.7 ± 7.260.25
IMR corrected, mean ± SD19.7 ± 8.5117.5 ± 7.250.28
Tmn during rest, sec, mean ± SD0.91 ± 0.400.92 ± 0.380.98
Tmn during hyperemia, sec, mean ± SD0.29 ± 0.120.26 ± 0.110.33
Pd, mmHg, mean ± SD70.7 ± 15.269.5 ± 12.50.75
Peak temperature, degree, median (IQR)−4.33 (−5.89, −2.84)−4.47 (−6.01, −3.75)0.23
TRT, sec, median (IQR)0.32 (0.26, 0.48)0.28 (0.20, 0.36)0.26
Derivative, degree/sec, median (IQR)9.95 (5.19, 21.5)17.3 (8.92, 24.3)0.16
CFR, mean ± SD3.15 ± 1.233.96 ± 1.580.03
FFR, mean ± SD0.90 ± 0.080.92 ± 0.070.52
FFR, median (IQR)0.91 (0.86, 0.97)0.91 (0.87, 0.98)0.61

IMR, index of microvascular resistance; IMR corrected, IMR corrected from influence of collateral supply; Tmn, mean transit time; Pd, distal pressure in a coronary; TRT, temperature recovery time; CFR, coronary flow reserve; FFR, fractional flow reserve.