Artificial Intelligence Enabled Fully Automated CMR Function Quantification for Optimized Risk Stratification in Patients Undergoing Transcatheter Aortic Valve Replacement
Table 5
Univariable and multivariable cox regression analyses including LVEF for prediction of CV mortality.
Variable
Hazard ratio (95% CI)
value
Univariable models
Age (Y)
1.074 (0.978–1.178)
0.135
Sex (male)
1.195 (0.438–3.261)
0.727
BMI (kg/m2)
1.090 (1.001–1.187)
0.048
Hypertension (present)
1.054 (0.240–4.623)
0.944
Diabetes mellitus (present)
2.196 (0.846–5.700)
0.106
Dyslipidaemia (present)
0.953 (0.347–2.618)
0.925
Coronary artery disease (present)
1.888 (0.614–5.811)
0.268
Atrial fibrillation (present)
2.372 (0.907–6.198)
0.078
Stroke/TIA (present)
0.816 (0.186–3.573)
0.787
COPD (present)
3.090 (1.005–9.501)
0.049
Automated LVEF (%)
0.967 (0.939–0.995)
0.022
LVEF (%)
0.970 (0.943–0.997)
0.032
Automated LV SVI (ml/m2)
0.996 (0.952–1.042)
0.859
LV SVI (ml/m2)
0.999 (0.961–1.039)
0.965
Multivariable models
Model 1a
Automated LVEF (%)
0.963 (0.933–0.995)
0.024
BMI (kg/m2)
1.130 (1.029–1.241)
0.011
COPD (present)
2.277 (0.691–7.507)
0.451
Model 1b
LVEF (%)
0.968 (0.938–0.999)
0.043
BMI (kg/m2)
1.126 (1.025–1.237)
0.013
COPD (present)
2.400 (0.718–8.014)
0.155
Model 2a
Automated LVEF (%)
0.954 (0.920–0.989)
0.011
BMI (kg/m2)
1.162 (1.024–1.320)
0.020
COPD (present)
1.718 (0.414–7.123)
0.456
Age (Y)
2.231 (0.742–6.704)
0.153
Diabetes mellitus (present)
2.231 (0.742–6.704)
0.153
Hypertension (present)
2.128 (0.397–11.417)
0.378
Dyslipidaemia (present)
0.662 (0.209–2.090)
0.482
Coronary artery disease (present)
1.363 (0.391–4.747)
0.627
Model 2b
LVEF (%)
0.962 (0.929–0.996)
0.027
BMI (kg/m2)
1.139 (1.014–1.280)
0.028
COPD (present)
2.000 (0.494–8.102)
0.331
Age (Y)
1.113 (0.345–4.406)
0.055
Diabetes mellitus (present)
2.385 (0.798–7.121)
0.120
Hypertension (present)
1.846 (0.356–9.578)
0.465
Dyslipidaemia (present)
0.655 (0.209–2.055)
0.468
Coronary artery disease (present)
1.233 (0.345–4.406)
0.747
BMI: body mass Index; TIA: transient ischemic attack; COPD: chronic obstructive pulmonary disease; LVEF: left ventricular ejection fraction; LV SVI: left ventricular stroke volume index
