Research Article
Prognostic Value of Combining Apelin-12 and Estimated Glomerular Filtration Rate in Patients with ST-Segment Elevation Myocardial Infarction
Table 1
Characteristics of patients.
| | | All patients (N = 460) | A (N = 70) | B (N = 154) | C (N = 158) | D (N = 78) | value |
| | Age | 62.9 ± 11.9 | 66.3 ± 11.1 | 59.3 ± 12.1 | 66.4 ± 11.1 | 59.9 ± 11.1 | <0.001 | | Sex | | | | | | <0.001 | | Male | 353 (76.7%) | 48 (68.6%) | 137 (89.0%) | 99 (62.7%) | 69 (88.5%) | | | Female | 107 (23.3%) | 22 (31.4%) | 17 (11.0%) | 59 (37.3%) | 9 (11.5%) | | | HR | 76.9 ± 17.2 | 78.7 ± 18.2 | 77.4 ± 16.0 | 75.9 ± 18.6 | 76.6 ± 15.3 | 0.694 | | SBP | 132 ± 27.2 | 134 ± 28.8 | 131 ± 27.8 | 131 ± 27.0 | 134 ± 24.7 | 0.693 | | Anterior wall MI | | | | | | 0.129 | | No | 231 (50.2%) | 29 (41.4%) | 74 (48.1%) | 81 (51.3%) | 47 (60.3%) | | | Yes | 229 (49.8%) | 41 (58.6%) | 80 (51.9%) | 77 (48.7%) | 31 (39.7%) | | | Killip grade | | | | | | 0.165 | | I | 348 (75.7%) | 46 (65.7%) | 122 (79.2%) | 122 (77.2%) | 58 (74.4%) | | | ≥II | 112 (24.3%) | 24 (34.3%) | 32 (20.8%) | 36 (22.8%) | 20 (25.6%) | | | DM | | | | | | 0.913 | | No | 312 (67.8%) | 48 (68.6%) | 103 (66.9%) | 110 (69.6%) | 51 (65.4%) | | | Yes | 148 (32.2%) | 22 (31.4%) | 51 (33.1%) | 48 (30.4%) | 27 (34.6%) | | | HTN | | | | | | 0.754 | | No | 196 (42.6%) | 33 (47.1%) | 61 (39.6%) | 68 (43.0%) | 34 (43.6%) | | | Yes | 264 (57.4%) | 37 (52.9%) | 93 (60.4%) | 90 (57.0%) | 44 (56.4%) | | | Previous MI | | | | | | 0.904 | | No | 405 (88.0%) | 61 (87.1%) | 137 (89.0%) | 140 (88.6%) | 67 (85.9%) | | | Yes | 55 (12.0%) | 9 (12.9%) | 17 (11.0%) | 18 (11.4%) | 11 (14.1%) | | | Apelin-12 | 0.76 (0.60–1.00) | 0.64 (0.56–0.71) | 0.58 (0.48–0.66) | 1.03 (0.90–1.22) | 0.88 (0.82–1.06) | <0.001 | | WBC | 10.1 ± 3.65 | 9.96 ± 4.19 | 10.3 ± 3.74 | 9.68 ± 3.45 | 10.5 ± 3.27 | 0.265 | | Neutrophils | 75.7 ± 11.5 | 77.4 ± 11.2 | 74.8 ± 11.8 | 76.3 ± 11.7 | 74.7 ± 11.0 | 0.310 | | Hemoglobin | 144 ± 17.2 | 145 ± 17.7 | 144 ± 17.1 | 143 ± 17.9 | 143 ± 15.7 | 0.848 | | Platelet | 232 ± 56.3 | 239 ± 57.2 | 230 ± 56.1 | 230 ± 55.4 | 234 ± 58.0 | 0.642 | | Albumin | 38.0 (35.0–41.0) | 39.0 (35.0–41.2) | 38.0 (35.0–40.9) | 38.0 (35.1–40.6) | 38.0 (34.0–40.8) | 0.636 | | TC | 5.66 ± 1.09 | 5.91 ± 1.22 | 5.67 ± 0.99 | 5.58 ± 1.13 | 5.62 ± 1.08 | 0.186 | | TG | 0.99 (0.55–1.54) | 0.98 (0.52–1.54) | 1.10 (0.55–1.75) | 0.90 (0.55–1.39) | 0.93 (0.58–1.55) | 0.441 | | HDL | 1.20 ± 0.27 | 1.24 ± 0.30 | 1.20 ± 0.26 | 1.19 ± 0.28 | 1.21 ± 0.24 | 0.532 | | LDL | 3.00 (2.49–3.60) | 3.22 (2.59–3.84) | 3.01 (2.50–3.63) | 2.81 (2.40–3.38) | 3.18 (2.41–3.89) | 0.009 | | FBG | 7.67 ± 2.54 | 7.36 ± 2.38 | 8.02 ± 2.66 | 7.51 ± 2.49 | 7.59 ± 2.47 | 0.196 | | Urea nitrogen | 6.73 ± 2.07 | 6.58 ± 2.08 | 6.65 ± 2.04 | 6.96 ± 2.00 | 6.54 ± 2.26 | 0.378 | | Creatinine | 75.0 (62.0–86.0) | 86.0 (79.2–90.2) | 59.0 (52.0–69.0) | 85.6 (80.0–92.5) | 65.9 (58.2–71.8) | <0.001 | | Uric acid | 337 ± 73.9 | 355 ± 81.6 | 330 ± 76.2 | 342 ± 69.7 | 325 ± 67.4 | 0.044 | | eGFR | 94.1 (77.8–119) | 79.2 (72.4–85.3) | 125 (106–145) | 76.9 (65.3–84.0) | 110 (101–125) | <0.001 | | CK-MB | 106 (45.8–195) | 94.5 (42.0–172) | 106 (48.0–212) | 108 (50.0–190) | 132 (38.2–194) | 0.668 | | cTnI | 13.9 (4.36–29.0) | 13.3 (6.04–29.5) | 15.5 (5.01–30.0) | 13.9 (3.50–27.3) | 12.7 (2.98–27.4) | 0.701 | | Pathological Q wave | | | | | | 0.080 | | No | 239 (52.0%) | 34 (48.6%) | 75 (48.7%) | 95 (60.1%) | 35 (44.9%) | | | Yes | 221 (48.0%) | 36 (51.4%) | 79 (51.3%) | 63 (39.9%) | 43 (55.1%) | | | Gensini score | 72.1 ± 32.2 | 73.0 ± 33.7 | 74.5 ± 32.0 | 66.9 ± 31.4 | 77.2 ± 31.8 | 0.069 | | Culprit vessels | | | | | | 0.029 | | LAD | 230 (50.0%) | 42 (60.0%) | 76 (49.4%) | 80 (50.6%) | 32 (41.0%) | | | LCX | 72 (15.7%) | 9 (12.9%) | 30 (19.5%) | 15 (9.49%) | 18 (23.1%) | | | RCA | 158 (34.3%) | 19 (27.1%) | 48 (31.2%) | 63 (39.9%) | 28 (35.9%) | | | Stent number | 1.38 ± 0.54 | 1.37 ± 0.62 | 1.32 ± 0.50 | 1.43 ± 0.57 | 1.38 (0.52) | 0.399 |
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