Prognostic Value of Combining Apelin-12 and Estimated Glomerular Filtration Rate in Patients with ST-Segment Elevation Myocardial Infarction

Table 2

Univariate and multivariate Cox regression.

Variables	Univariate Cox			Multivariate Cox
	HR	95% CI		HR	95% CI
Age	1.04	1.02–1.06	<0.001	1.03	1.01–1.05	8.00E-04
Sex
Female vs. male	1.27	0.85–1.90	0.240
HR	1.01	1.00–1.02	0.043	1.00	0.99–1.01	0.4481
SBP	1.00	0.99–1.01	0.809
Anterior wall MI
Yes vs. no	1.71	1.18–2.47	0.005	1.57	1.06–2.32	0.0243
Killip grade
II vs. I	1.89	1.29–2.76	0.001	1.49	0.99–2.24	0.0557
DM
Yes vs. no	1.12	0.77–1.63	0.562
HTN
Yes vs. no	1.18	0.81–1.70	0.391
Previous MI
Yes vs. no	1.53	0.93–2.49	0.091
Apelin-12	0.22	0.11–0.44	<0.001
WBC	1.03	0.98–1.09	0.183
Neutrophils	1.01	0.99–1.03	0.203
Hemoglobin	0.98	0.97–0.99	0.001	0.99	0.98–1.00	0.0944
Platelet	1.00	1.00–1.01	0.080
Albumin	1.00	0.95–1.04	0.853
TC	1.20	1.04–1.40	0.014	1.23	1.05–1.44	0.0121
TG	0.92	0.73–1.16	0.467
HDL	2.11	1.07–4.17	0.031	1.06	0.53–2.11	0.8639
LDL	1.06	0.83–1.35	0.659
FBG	1.00	0.93–1.07	0.922
Urea nitrogen	1.01	0.93–1.10	0.832
Creatinine	1.00	1.00–1.01	0.31
Uric acid	1.00	1.00–1.02	0.647
eGFR	0.99	0.98–1.00	0.004
CK-MB	1.00	1.00–1.03	0.475
cTnI	1.01	1.00–1.03	0.092
Pathological Q wave
Yes vs. no	1.72	1.19–2.48	0.004	1.73	1.18–2.53	0.0047
Gensini score	1.00	1.00–1.01	0.141
Culprit vessels
LAD	ref	ref	ref
LCX	0.88	0.52–1.48	0.621
RCA	0.80	0.53–1.20	0.281
Stent number	0.88	0.62–1.25	0.472
Group
Group A	Ref	Ref	Ref	Ref	Ref	Ref
Group B	0.49	0.30–0.79	0.003	0.6	0.37–0.98	0.0399
Group C	0.51	0.32–0.83	0.006	0.55	0.34–0.89	0.0151
Group D	0.24	0.12–0.49	<0.001	0.27	0.13–0.57	5.00E-04