Individualized Approaches for Patients with Non-Obstructive Coronary Artery Disease
1Centre of Postgraduate Medical Education, Warsaw, Poland
2University of Warmia and Mazury, Olsztyn, Poland
3Medical University of Silesia, Wrocław, Poland
4Costa del Sol Hospital, Marbella, Spain
Individualized Approaches for Patients with Non-Obstructive Coronary Artery Disease
Description
Ischemia with non-obstructive coronary arteries (INOCA) is an increasingly concerning problem. Up to 20-30% of patients referring to coronary angiography have normal coronary arteries, however this does not mean these patients are healthy and sound. Patients with INOCA are characterized not only by impaired quality of life but also by worsened prognosis.
The definition of myocardial infarction is not the same as it was 50 years ago - according to the fourth universal definition of myocardial infarction (MI) developed by the European Society of Cardiology, MI can be recognized by a ‘rise and/or fall’ of troponin associated with at least one of the following: symptoms of ischemia, electrocardiographic changes suggesting new ischemia, evidence of new loss of viable myocardium or new regional wall motion abnormalities or the presence of intra-coronary thrombus in angiography or autopsy. In such cases, myocardial infarction with non-obstructive coronary arteries (MINOCA) can be identified. As such, there is increasing interest in the proper management of these patients, including in catheterization laboratories, and in new possibilities, both non-invasive and invasive, including provocative acetylcholine tests and microvascular resistance assessments performed in one procedure.
This Special Issue aims to expand our knowledge on recent advances in the pathogenesis, diagnosis, prognosis, and management of INOCA and MINOCA. We welcome both original research and review articles.
Potential topics include but are not limited to the following:
- Personalized medicine for ischemia with non-obstructive coronary arteries
- Ischemia with non-obstructive coronary arteries
- Myocardial infarction with non-obstructive coronary arteries
- Microcirculation dysfunction
- Index of microvascular resistance
- New pharmacological options in INOCA
- Prognosis improvement in INOCA
- Provocative acetylcholine tests
- Coronary vasospasm
- Quality of life in INOCA patients
- Non-invasive cardiac imaging in MINOCA patients