Novel Conjugates of 1,3-Diacylglycerol and Lipoic Acid: Synthesis, DPPH Assay, and RP-LC-MS-APCI Analysis

Table 1

Free radical scavenging activity of DHLA and DODHLA.

Compound	Efficient concentration (EC50)^a   ± SD	Antradical power (ARP)^b  ± SD	No. moles DPPH reduced/mole of antioxidant ± SD
DHLA	0.39 ± 0.04	2.56 ± 0.24	1.28 ± 0.12
DODHLA	0.22 ± 0.03	4.55 ± 0.55	2.27 ± 0.27

DHLA: dihydrolipoic acid; DODHLA: 1,3-dioleoyl-2dihydrolipoyl-sn-glycerol.
^aEfficient Concentration = EC₅₀.
^bARP value was calculated from 1/ EC₅₀, the larger the ARP the more efficient the antioxidant (see [29]).