Review Article

Membrane Fusion Induced by Small Molecules and Ions

Table 1

Calculated amount of Ca2+ bound per PS in mixed PS/PC membranes [60].

Vesicle composition (PS : PC)Calculated tightly bound Ca2+ at various Ca2+ concentrations (in mM)Na+ bulk concentration
(in mM)
0.71.02.03.05.010.0

Pure PS0.440.440.440.440.450.455
 4 : 10.430.430.440.440.440.445
 2 : 10.420.430.440.440.440.445
 3 : 20.410.410.420.420.430.435
 1 : 10.400.400.410.420.430.435
 2 : 30.380.390.400.400.410.425
 1 : 40.320.330.350.360.370.385

Pure PS0.320.350.380.390.410.43100
 4 : 10.300.330.360.380.400.42100
 2 : 10.280.320.350.370.390.41100
 3 : 20.270.310.340.360.380.40100
 1 : 10.250.290.330.350.370.39100
 2 : 30.230.260.310.330.350.38100
 1 : 40.150.190.240.260.300.34100

Pure PS0.110.160.210.250.290.34500
 4 : 10.100.140.200.230.270.33500
 2 : 10.090.120.180.220.260.32500
 3 : 20.080.120.170.210.250.31500
 1 : 10.070.110.160.190.240.30500
 2 : 30.060.090.140.180.220.28500
 1 : 40.040.060.100.130.180.25500