Review Article
Membrane Fusion Induced by Small Molecules and Ions
Table 1
Calculated amount of Ca
2+ bound per PS in mixed PS/PC membranes [
60].
| Vesicle composition (PS : PC) | Calculated tightly bound Ca2+ at various Ca2+ concentrations (in mM) | Na+ bulk concentration (in mM) | 0.7 | 1.0 | 2.0 | 3.0 | 5.0 | 10.0 |
| Pure PS | 0.44 | 0.44 | 0.44 | 0.44 | 0.45 | 0.45 | 5 | 4 : 1 | 0.43 | 0.43 | 0.44 | 0.44 | 0.44 | 0.44 | 5 | 2 : 1 | 0.42 | 0.43 | 0.44 | 0.44 | 0.44 | 0.44 | 5 | 3 : 2 | 0.41 | 0.41 | 0.42 | 0.42 | 0.43 | 0.43 | 5 | 1 : 1 | 0.40 | 0.40 | 0.41 | 0.42 | 0.43 | 0.43 | 5 | 2 : 3 | 0.38 | 0.39 | 0.40 | 0.40 | 0.41 | 0.42 | 5 | 1 : 4 | 0.32 | 0.33 | 0.35 | 0.36 | 0.37 | 0.38 | 5 |
| Pure PS | 0.32 | 0.35 | 0.38 | 0.39 | 0.41 | 0.43 | 100 | 4 : 1 | 0.30 | 0.33 | 0.36 | 0.38 | 0.40 | 0.42 | 100 | 2 : 1 | 0.28 | 0.32 | 0.35 | 0.37 | 0.39 | 0.41 | 100 | 3 : 2 | 0.27 | 0.31 | 0.34 | 0.36 | 0.38 | 0.40 | 100 | 1 : 1 | 0.25 | 0.29 | 0.33 | 0.35 | 0.37 | 0.39 | 100 | 2 : 3 | 0.23 | 0.26 | 0.31 | 0.33 | 0.35 | 0.38 | 100 | 1 : 4 | 0.15 | 0.19 | 0.24 | 0.26 | 0.30 | 0.34 | 100 |
| Pure PS | 0.11 | 0.16 | 0.21 | 0.25 | 0.29 | 0.34 | 500 | 4 : 1 | 0.10 | 0.14 | 0.20 | 0.23 | 0.27 | 0.33 | 500 | 2 : 1 | 0.09 | 0.12 | 0.18 | 0.22 | 0.26 | 0.32 | 500 | 3 : 2 | 0.08 | 0.12 | 0.17 | 0.21 | 0.25 | 0.31 | 500 | 1 : 1 | 0.07 | 0.11 | 0.16 | 0.19 | 0.24 | 0.30 | 500 | 2 : 3 | 0.06 | 0.09 | 0.14 | 0.18 | 0.22 | 0.28 | 500 | 1 : 4 | 0.04 | 0.06 | 0.10 | 0.13 | 0.18 | 0.25 | 500 |
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