Impact of oxLDL on Cholesterol-Rich Membrane Rafts
Figure 5
Impact of oxidized low-density lipoprotein (oxLDL) on lipid packing of membrane domains in bovine aortic endothelial cells. (a) Typical general polarization (GP) images of control cells (Ctrl), MβCD-treated cells, oxLDL-treated cells (oxLDL), or cells exposed to oxLDL and MβCD-cholesterol sequentially (oxLDLChol). Scale bar is 5.6 μm. (b) zoom-in representative regions of the GP images shown in (a) (the zoomed regions are ). Scale bar is 1 μm. (c) GP histograms for the four experimental cell populations (dots) fitted by a two-Gaussian distribution with the curve representing ordered domains (red) and the curve representing fluid domains (green). The sum of the Gaussians is shown in black. Adapted from [25].
