Hepatic Metabolic, Inflammatory, and Stress-Related Gene Expression in Growing Mice Consuming a Low Dose of Trans-10, cis-12-Conjugated Linoleic Acid

Table 5

Hepatic expression of genes related to lipid catabolism in mice fed control or the control supplemented with trans-10, cis-12-CLA (CLA). There were no significant interactions of treatment × time. Therefore, the results are presented according to main effects (treatment and time).

Gene	Treatment		Time		SEM
	Control	CLA	Week 2	Week 6
Fatty acid oxidation and energy metabolism
Aacs	−0.21	−0.29	−0.26	−0.25	0.31
Acox1	−0.22^a	0.13^b	−0.08	−0.003	0.14
Bdh1	−0.20^a	0.13^b	0.06	−0.12	0.12
Cpt1a	−0.43	−0.32	−0.36	−0.39	0.14
Insig1	−0.79	0.35	−0.23	−0.20	0.45
Mlycd	0.001	−0.17	−0.07	−0.11	0.10
Pdk4	−1.85^a	0.47^b	−0.81	−0.57	0.50
Ucp2	−0.31^a	0.15^b	−0.04	−0.11	0.10
Hmgcs2	−0.16^a	0.13^b	0.10^a	−0.13^b	0.11
Transcription regulation
Ppar α	−0.33	−0.19	−0.23	−0.30	0.12

^a,bMeans within each main effect (treatment and time) with different superscripts differ (𝑃≤0.05).
SEM: the largest standard error of the mean is shown.