Research Article

Lipid Peroxidation and Paraoxonase-1 Activity in Celiac Disease

Table 1

Clinical characteristics and levels of serum lipids in healthy subjects, celiac patients at diagnosis (CD patients) and celiac patients treated with a gluten-free diet (GFD patients). Data are given as means ± S.D.

Healthy subjects ( 𝑛 = 2 5 )Celiac patients ( 𝑛 = 2 7 )
CD patients( 𝑛 = 1 1 )GFD patients ( 𝑛 = 1 6 )

Serum t-TGa (U/mL) 0 . 4 ± 0 . 2 1 0 8 . 2 ± 3 5 . 9 * 2 . 3 ± 1 . 9 *#
Damage of intestinal mucosab0 4 . 4 ± 0 . 6 * 1 . 4 ± 0 . 7 *#
Serum triglycerides (mg/dL) 8 7 . 1 4 0 . 5 ± 6 1 . 3 ± 2 3 . 5 7 1 . 2 ± 4 8 . 2
Serum cholesterol (mg/dL) 1 8 6 . 6 ± 4 3 . 4 1 5 4 . 1 ± 2 7 . 6 1 7 7 . 1 ± 4 2 . 6
Serum HDL-cholesterol (mg/dL) 5 6 . 3 ± 1 3 . 4 5 1 . 1 ± 7 . 9 5 4 . 6 ± 8 . 7
Serum LDL-cholesterol (mg/dL) 1 1 3 . 2 ± 2 3 . 7 9 0 . 6 ± 1 6 . 1 1 0 8 . 8 ± 2 6 . 2

at-TG: antitransglutaminaseantibodies. bDamage of intestinal mucosa was classified according to Marsh parameters and each stage was given a score from 0 (normal mucosa) to 5 (total villous atrophy).
* 𝑃 < 0 . 0 0 1 versus healthy subjects; # 𝑃 < 0 . 0 5 versus CD patients.