Journal of Lipids

Research Article

Paraoxonase 1 Phenotype and Mass in South Asian versus Caucasian Renal Transplant Recipients

Table 1

ParameterAll patients
South Asian ( š‘ = 4 3 )Caucasian ( š‘ = 8 6 ) š‘ƒ -value
Age at transplant (years) 4 8 Ā± 1 1 5 0 Ā± 1 1 NS
Age at study visit (years) 5 0 Ā± 1 0 5 2 Ā± 1 1 NS
Gender (M/F)30/1360/26NS
Time post transplant (months) 6 5 Ā± 4 7 7 1 Ā± 4 8 NS
BMI (kg/m2) 2 6 . 9 Ā± 4 . 1 2 8 . 0 Ā± 6 . 0 NS
Total cholesterol (mmol/L) 4 . 8 Ā± 1 . 6 4 . 4 Ā± 1 . 1 NS
HDL cholesterol (mmol/L) 1 . 1 Ā± 0 . 4 1 . 1 Ā± 0 . 3 NS
LDL cholesterol (mmol/L) 3 . 1 Ā± 1 . 2 2 . 7 Ā± 0 . 9 0.07
Triglycerides (mmol/L) 1 . 8 Ā± 0 . 9 1 . 6 Ā± 0 . 7 NS
VLDL cholesterol 0 . 5 Ā± 0 . 4 0 . 5 Ā± 0 . 3 NS
VLDL triglycerides 1 . 3 Ā± 0 . 8 1 . 2 Ā± 0 . 6 NS
ApoAI (mg/L) 1 . 4 Ā± 0 . 3 1 . 4 Ā± 0 . 3 NS
ApoB (mg/L) 0 . 9 Ā± 0 . 3 0 . 8 Ā± 0 . 2 NS
eGFR by MDRD (mL/min/1.73ā€‰m2) 6 6 Ā± 2 1 6 0 Ā± 1 9 NS
Cystatin C (mg/L) 1 . 2 Ā± 0 . 4 1 . 2 Ā± 0 . 3 NS
eGFR by Cystatin C (mL/min/1.73ā€‰m2) 6 5 Ā± 2 2 6 2 Ā± 2 0 NS
C-reactive protein (mg/L) 4 . 5 Ā± 7 . 9 6 . 0 Ā± 1 3 NS
PON1 (Ī¼g/mL) median (quartiles)100 (84, 122)105 (81.7, 127)NS
PON1 arylesterase (U/mL) median (quartiles)79.5 (72.7, 90.4)81.4 (72.2, 91.8)NS
PON1 CMPA activity (U/mL) median (quartiles)19.4 (15.3, 26.8)16.5 (13.6, 22.8)0.08
PON1 arylesterase activity salt stimulated (U/mL) median (quartiles)45.4 (35.0, 54.7)47.8 (37.3, 56.7)NS