Dietary Omega-3 Fatty Acids Do Not Change Resistance of Rat Brain or Liver Mitochondria to and/or Prooxidants
Figure 4
Omega-3 PUFA enriched diet does not affect the sensitivity of brain mitochondria respiratory parameters to IsoKs. (a) Respiratory parameters measured in different metabolic states state 2 (), state 3 (), state 4 (), FCCP-stimulated respiration (). Glutamate/malate was used as the substrate. IsoKs were added to mitochondria after the addition of substrate. (b) The dependence of the RCRs on omega-3 dietary content. The data are expressed in μmol O2/min/mg protein and are the mean ± SEM, . Statistical significance in oxygen consumption between tested samples was determined by a two-sample t-test.
