Journal of Lipids / 2012 / Article / Fig 1

Review Article

Nuclear Receptor Variants in Liver Disease

Figure 1

Schematic depiction of NR action in hepatocytes demonstrating a reduction in complexity and an increase in penetrance of genetic variants from the sinus to the canaliculus. Squares represent metabolic compounds such as triglycerides, cholesterol, fatty acids, and phospholipids; triangles represent bile salts; stars represent toxins; large semi-circles symbolise nuclear receptors, and circles stand for metabolic enzymes.

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