Grape Seed Proanthocyanidin Rescues Rats from Steatosis:  A Comparative and Combination Study with Metformin

<table>Effect of GSP and MET on mRNA expression of lipogenesis markers in liver of experimental animals. mRNA of SREBP-1c (a) and mRNA of HMG CoA reductase (b). Experiments were performed in triplicates, and the data expressed are means ± S.D. of 3 rats from each group. The obtained Ct values of the test genes were normalized with GAPDH and expressed in bars as fold change. Statistical significance between the groups, denoted by different alphabets, was determined by one-way ANOVA of significance set at <svg height="11.375" id="M12" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Journal of Lipids

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Figure 5

Figure 5: Grape Seed Proanthocyanidin Rescues Rats from Steatosis:  A Comparative and Combination Study with Metformin 