Grape Seed Proanthocyanidin Rescues Rats from Steatosis: A Comparative and Combination Study with Metformin
Figure 9
Histology of liver stained using Oil Red O. Sections from liver tissue of CON (a) and CON + GSP (f) show liver sections with normal architecture. HFFD-fed rats show severe steatosis and ballooning degeneration of hepatocytes (b). GSP administration to HFFD-fed rats show, minimal amount of steatosis (c), whereas MET administration to HFFD-fed rats shows moderate steatosis (d). HFFD + GSP + MET show hepatocytes with occasional areas of steatosis (e). (Black arrows indicate Oil Red stain accumulation.)
