The Impairment of Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on Serum Amyloid A
Table 1
Hepatic gene expression levels in control and LPS-treated mice.
Gene
WT
SAAKO
PBS
LPS
PBS
LPS
SR-BI
1.00 ± 0.06
0.42 ± 0.05***
0.77 ± 0.06
0.56 ± 0.07*
Cyp7A1
1.00 ± 0.20
0.28 ± 0.15
1.73 ± 0.35
0.94 ± 0.30
ABCA1
1.00 ± 0.06
1.22 ± 0.12
1.06 ± 0.11
1.01 ± 0.11
ABCG1
1.00 ± 0.05
0.43 ± 0.04***
0.99 ± 0.08
0.47 ± 0.06***
ABCG5
1.00 ± 0.07
0.38 ± 0.03***
1.24 ± 0.18
0.41 ± 0.04***
ABCG8
1.00 ± 0.10
0.23 ± 0.02***
1.24 ± 0.16
0.28 ± 0.04***
ABCB11
1.00 ± 0.05
0.22 ± 0.06***
0.97 ± 0.11
0.42 ± 0.09***
Values are expressed relative to control WT mice after normalization to GAPDH mRNA. Data represent mean ± SEM, .
*
P < 0.05, ***P < 0.001, compared to corresponding PBS-treated mice.
