Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice
Figure 3
PCSK9 response in C57BL/6 mice assigned to a high-fat (HF) or a high-fat/exercise (HF + EX) group for 8 weeks. (a) Hepatic PCSK9 mRNA expression; (b) hepatic PCSK9 protein abundance; (c) plasma PCSK9 (ng/mL); and (d) Pearson’s product-moment correlation between plasma PCSK9 and non-HDL cholesterol concentrations. All expression data are normalized to -actin and expressed relative to the HF group; values are mean ± SE, ; denotes a significant difference (). Representative PCSK9 protein expression blots were cropped from the same membrane.
