Apolipoproteins A-I, B, and C-III and Obesity in Young Adult Cherokee
Table 1
Mean values, standard deviations, and differences (, bold type) between metabolically healthy obese (MHO) individuals, defined as those who are obese without any of four abnormal National Cholesterol Education Program (NCEP) metabolic syndrome components after excluding waist circumference, and metabolically abnormal obese (MAO) individuals defined as having one or more of the four abnormal criteria. Obesity was defined as body mass index (BMI) ≥ 30 for young adult Cherokee aged 20–40.
MHO ()
MAO ()
Mean
STD
Mean
STD
Obesity
Male
56.1%
41.1%
0.0643
BMI
33.87
3.87
36.81
6.90
0.0096
Waist (cms)
102.95
10.78
109.43
13.54
0.0006
Waist : height
0.62
0.05
0.66
0.09
0.0022
Blood pressure (mm Hg)
SBP
118.59
7.57
122.88
13.01
0.0009
DBP
75.55
6.9676
79.41
9.6968
0.0007
Insulin resistance
FPG (mmol/L)
4.55
0.55
4.85
0.62
0.0047
Insulin (µU/ml)
114.60
62.45
181.24
116.0
0.0002
4.59
0.57
5.03
0.57
<0.0001
HOMA-IR
3.88
2.23
6.58
4.51
0.0001
Lipids (mmol/L)
TC
4.37
0.87
4.42
0.89
0.8534
TG
0.87
0.36
1.42
0.80
<0.0001
4.25
0.4570
4.69
0.5366
<0.0001
LDL-C
2.65
0.81
2.83
0.78
0.2249
HDL-C
1.31
0.19
0.95
0.22
<0.0001
Non-HDL-C
3.05
0.88
3.47
0.88
0.0040
Apolipoproteins (µmol/L)
ApoB
1.56
0.37
1.75
0.40
0.0023
ApoA-I
2.56
0.31
2.15
0.32
<0.0001
ApoB : apoA-I
0.62
0.1542
0.83
0.2046
<0.0001
LpA-1
0.57
0.08
0.47
0.09
<0.0001
LpA-1 : A-II
1.99
0.24
1.68
0.24
<0.0001
Non-HDL-apoC-III
0.06
0.03
0.09
0.05
0.0001
HDL-apoC-III
0.09
0.02
0.09
0.02
0.4069
, value for difference between the two groups after adjusting for age and gender, and significant values () are in bold font; STD, standard deviation.
