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Journal of Lipids
Volume 2017 (2017), Article ID 8479482, 9 pages
https://doi.org/10.1155/2017/8479482
Research Article

Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL

1Department of Chemistry, Vanderbilt University, VU Station B, Nashville, TN 37235-1822, USA
2Vanderbilt Institute for Integrative Biosystems Research and Education, Vanderbilt University, Nashville, TN 37235-1809, USA
3Novartis Institutes for Biomedical Research, 220 Massachusetts Ave. 360C, Cambridge, MA 02139, USA

Correspondence should be addressed to David E. Cliffel

Received 13 February 2017; Accepted 4 May 2017; Published 31 May 2017

Academic Editor: Zufeng Ding

Copyright © 2017 Danielle W. Kimmel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. Yoshida, N. Kondratenko, S. Green, D. Steinberg, and O. Quehenberger, “Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor,” Biochemical Journal, vol. 334, no. 1, pp. 9–13, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. T. Navarra, S. Del Turco, S. Berti, and G. Basta, “The lectin-like oxidized low-density lipoprotein receptor-1 and its soluble form: Cardiovascular implications,” Journal of Atherosclerosis and Thrombosis, vol. 17, no. 4, pp. 317–331, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. H. Moriwaki, N. Kume, H. Kataoka et al., “Expression of lectin-like oxidized low density lipoprotein receptor-1 in human and murine macrophages: upregulated expression by TNF-α,” FEBS Letters, vol. 440, no. 1-2, pp. 29–32, 1998. View at Publisher · View at Google Scholar · View at Scopus
  4. N. Kume, H. Moriwaki, H. Kataoka et al., “Inducible expression of LOX-1, a novel receptor for oxidized ldl, in macrophages and vascular smooth muscle cells,” in Atherosclerosis V: The Fifth Saratoga Conference, F. Numano and M. A. Gimbrone, Eds., vol. 902, pp. 323–327, New York Acad Sciences, New York, NY, USA, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. D. W. Kimmel, W. P. Dole, and D. E. Cliffel, “In preparation for tox let,” 2012.
  6. S. Ogura, A. Kakino, Y. Sato et al., “LOX-1: The multifunctional receptor underlying cardiovascular dysfunction,” Circulation Journal, vol. 73, no. 11, pp. 1993–1999, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. D. P. Via, A. L. Plant, I. F. Craig, A. M. Gotto Jr., and L. C. Smith, “Metabolism of normal and modified low-density lipoproteins by macrophage cell lines of murine and human origin,” Biochimica et Biophysica Acta (BBA)—Lipids and Lipid Metabolism, vol. 833, no. 3, pp. 417–428, 1985. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Tanimoto, Y. Murata, M. Nomaguchi et al., “Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells,” FEBS Letters, vol. 508, no. 3, pp. 345–349, 2001. View at Publisher · View at Google Scholar · View at Scopus
  9. H. Hemmi, O. Takeuchi, T. Kawai et al., “A Toll-like receptor recognizes bacterial DNA,” Nature, vol. 408, pp. 740–745, 2000. View at Publisher · View at Google Scholar · View at Scopus