Research Article

Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL

Table 2

Metabolic lactate production of various LDL exposure to macrophages. Mean peak MAMP height changes and standard errors for each experimental condition during exposure. All values are calculated based on peak height versus 10 min average basal value prior to exposure. Terms in bold are representative of , indicating statistical significance.

Lactate
Native LDL (%)Low oxLDL (%)Medium oxLDL (%)High oxLDL (%)Intracel oxLDL (%)

1 µg/ml3.2 ± 0.681.42 ± 1.581.81 ± 1.31.54 ± 2.82.0 ± 2.1
p = 0.0022 = 0.3987 = 0.2047 = 0.6001 = 0.3875
10 µg/ml1.0 ± 1.00.39 ± 1.517.2 ± 20.00.91 ± 0.632.7 ± 0.66
= 0.3699 = 0.8039 = 0.4134 = 0.2198p = 0.0143
50 µg/ml0.47 ± 1.10.84 ± 0.160.38 ± 3.82.0 ± 1.88.1 ± 2.35
= 0.698p = 0.0040 = 0.9534 = 0.3012p = 0.0117
100 µg/ml4.0 ± 1.52.7 ± 1.11.21 ± 1.215.2 ± 4.297.03 ± 3.0
p = 0.0445p = 0.0441 = 0.379p = 0.0172p = 0.0438