Journal of Lipids / 2018 / Article / Tab 4

Research Article

Developing a Modified Low-Density Lipoprotein (M-LDL-C) Friedewald’s Equation as a Substitute for Direct LDL-C Measure in a Ghanaian Population: A Comparative Study

Table 4

Diagnosis performances of the various formulas.

FormulasCut-off pointAUC95 CISensitivity (95 CI)Specificity (95CI)NPVPPV

F-LDL-C2.920.800.78-.830.63(0.60-0.67)0.84(0.82-0.87)0.870.74
N-LDL-C2.920.810.78-.830.63(0.60-0.66)0.85(0.82-0.87)0.870.78
A-LDL-C2.960.77.75-.780.68(0.65-0.72)0.73(0.70-0.77)0.680.73
M-LDL-C3.230.81.78-.830.60(0.56-0.64)0.88(0.85-0.90)0.720.72

AUC: area under curve; CI: confidence interval; NPV: negative predictive value; PPV: positive predictive value; FLDL-C, LDL-C calculated by Friedewald’s formula; N-LDL-C, LDL-C calculated by Martin’s formula; A-LDL-C, LDL-C calculated by Anandaraja’s formula; M-LDL-C, LDL-C calculated by modified formula.

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