Developing a Modified Low-Density Lipoprotein (M-LDL-C) Friedewald’s Equation as a Substitute for Direct LDL-C Measure in a Ghanaian Population: A Comparative Study

Table 5

Pearson correlation coefficient (r) (bold) and coefficient of determination (R²) (italics) between formulas.

Formulas	F-LDL	N-LDL	A-LDL	M-LDL	D-LDL-C
F-LDL-C (mmol/L)		0.995	0.947	0.994	0.693
		<0.0001	<0.0001	<0.0001	<0.0001
N-LDL-C (mmol/L)	0.991		0.937	0.999	0.693
	<0.0001		<0.0001	<0.0001	<0.0001
A-LDL-C (mmol/L)	0.898	0.878		0.935	0.658
	<0.0001	<0.0001		<0.0001	<0.0001
M-LDL-C (mmol/L)	0.989	0.999	0.8743		0.693
	<0.0001	<0.0001	<0.0001		<0.0001
D-LDL-C (mmol/L)	0.481	0.480	0.434	0.481
	<0.0001	<0.0001	<0.0001	<0.0001

FLDL-C, LDL-C calculated by Friedewald’s formula; N-LDL-C, LDL-C calculated by Martin’s formula; A-LDL-C, LDL-C calculated by Anandaraja’s formula; M-LDL-C, LDL-C calculated by modified formula.