Journal of Lipids

Lipids and Lipoproteins in Atherosclerosis


Publishing date
15 Aug 2011
Status
Published
Submission deadline
15 Feb 2011

Lead Editor

1Institute of Biology, National Center for Scientific Research “Demokritos”, Agia Paraskevi, 15310 Athens, Greece

2Biomedical Research Foundation of the Academy of Athens, 11527 Athens; Department of Pharmacology, Medical School, University of Thessaly, 41110 Larissa, Greece

3Department of Occupational and Environmental Medicine, Linköping University Hospital, 58185 Linköping, Sweden


Lipids and Lipoproteins in Atherosclerosis

Description

Lipids have a variety of biological roles: they are components of cellular membranes, serve as energy stores, are fuel molecules, and are surface-active ingredients of lung surfactant. Furthermore, lipids and lipid derivatives are hormones and vitamins and in the form of bile salts solubilize dietary lipids. Lipids also participate in signal transduction and transcriptional regulation. The transport of lipids in the bloodstream is achieved by the packing of the lipid moieties into water-soluble lipoproteins. Lipoproteins are complexes of amphipathic proteins with lipids. Plasma lipoproteins have traditionally been grouped into five major classes, based on their buoyant density: chylomicrons, very low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL). Lipoproteins are synthesized and catabolized in three distinct pathways: the chylomicron pathway, the VLDL/IDL/LDL pathway, and the HDL pathway, all of which are metabolically interrelated. Several different proteins, including apolipoproteins, plasma enzymes, lipid transfer proteins, lipoprotein receptors, and lipid transporters participate in lipid and lipoprotein metabolism pathways and contribute to lipid homeostasis. Genetic alterations in any of the above proteins may affect cellular and plasma lipid levels and may lead to various diseases.

We invite authors to submit original research and review articles that seek to define the role of lipids and lipoproteins in health and diseases with emphasis given on their implication in atherosclerosis. Potential topics include, but are not limited to:

  • Role of enzymes and other proteins involved in the metabolism of lipids in cells, tissues, and circulation in relation to atherosclerosis
  • Role of lipids in signal transduction and transcriptional regulation in relation to atherosclerosis
  • Role of lipoproteins in the immune defense system
  • Lipidomic and proteomic technologies for detailed molecular characterization of lipoproteins composition
  • Physicochemical basis of apolipoprotein function
  • Dyslipidemias
  • Hypolipidemias
  • New pharmacological targets and novel therapies for prevention and treatment of atherosclerosis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jl/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 160104
  • - Editorial

Lipids and Lipoproteins in Atherosclerosis

Angeliki Chroni | George Leondaritis | Helen Karlsson
  • Special Issue
  • - Volume 2011
  • - Article ID 154672
  • - Research Article

Visceral Abdominal and Subfascial Femoral Adipose Tissue Have Opposite Associations with Liver Fat in Overweight and Obese Premenopausal Caucasian Women

Paulo M. Rocha | José T. Barata | ... | Luís B. Sardinha
  • Special Issue
  • - Volume 2011
  • - Article ID 532145
  • - Research Article

LysoPC and PAF Trigger Arachidonic Acid Release by Divergent Signaling Mechanisms in Monocytes

Janne Oestvang | Marit W. Anthonsen | Berit Johansen
  • Special Issue
  • - Volume 2011
  • - Article ID 702853
  • - Review Article

Homocysteine as a Risk Factor for Atherosclerosis: Is Its Conversion to S-Adenosyl-L-Homocysteine the Key to Deregulated Lipid Metabolism?

Oksana Tehlivets
  • Special Issue
  • - Volume 2011
  • - Article ID 575840
  • - Review Article

Lipid Abnormalities and Cardiometabolic Risk in Patients with Overt and Subclinical Thyroid Disease

Melpomeni Peppa | Grigoria Betsi | George Dimitriadis
  • Special Issue
  • - Volume 2011
  • - Article ID 271062
  • - Research Article

The Apolipoprotein C-I Content of Very-Low-Density Lipoproteins Is Associated with Fasting Triglycerides, Postprandial Lipemia, and Carotid Atherosclerosis

John-Bjarne Hansen | José A. Fernández | ... | Ellisiv B. Mathiesen
  • Special Issue
  • - Volume 2011
  • - Article ID 549137
  • - Research Article

LDL-C/HDL-C Ratio Predicts Carotid Intima-Media Thickness Progression Better Than HDL-C or LDL-C Alone

Mika Enomoto | Hisashi Adachi | ... | Tsutomu Imaizumi
  • Special Issue
  • - Volume 2011
  • - Article ID 493720
  • - Research Article

Human Plasma Very Low-Density Lipoproteins Are Stabilized by Electrostatic Interactions and Destabilized by Acidic pH

Madhumita Guha | Olga Gursky
  • Special Issue
  • - Volume 2011
  • - Article ID 418313
  • - Review Article

The Dynamics of Oxidized LDL during Atherogenesis

Hiroyuki Itabe | Takashi Obama | Rina Kato
Journal of Lipids
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