Table of Contents
Journal of Medical Engineering
Volume 2017 (2017), Article ID 3409327, 20 pages
Review Article

Optical Coherence Tomography: Basic Concepts and Applications in Neuroscience Research

Notre Dame College, Motijheel Circular Road, Arambagh, Motijheel, Dhaka 1000, Bangladesh

Correspondence should be addressed to Mobin Ibne Mokbul

Received 26 April 2017; Revised 22 June 2017; Accepted 14 September 2017; Published 29 October 2017

Academic Editor: Nicusor Iftimia

Copyright © 2017 Mobin Ibne Mokbul. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Optical coherence tomography is a micrometer-scale imaging modality that permits label-free, cross-sectional imaging of biological tissue microstructure using tissue backscattering properties. After its invention in the 1990s, OCT is now being widely used in several branches of neuroscience as well as other fields of biomedical science. This review study reports an overview of OCT’s applications in several branches or subbranches of neuroscience such as neuroimaging, neurology, neurosurgery, neuropathology, and neuroembryology. This study has briefly summarized the recent applications of OCT in neuroscience research, including a comparison, and provides a discussion of the remaining challenges and opportunities in addition to future directions. The chief aim of the review study is to draw the attention of a broad neuroscience community in order to maximize the applications of OCT in other branches of neuroscience too, and the study may also serve as a benchmark for future OCT-based neuroscience research. Despite some limitations, OCT proves to be a useful imaging tool in both basic and clinical neuroscience research.