Optical Coherence Tomography: Basic Concepts and Applications in Neuroscience Research

Figure 3

3D ODT images of CBFv in mouse somatosensory cortex due to acute cocaine exposure. (a) Dynamic changes of 3D CBF networks (FOV: 3 × 3 × 1.8 mm³) in mouse somatosensory cortex in response to acute cocaine (30 mg/kg, i.p.). (b) En face and cross-sectional projections to show the flow dynamics in different vessels (e.g., 1–6) after cocaine. (c) Time-lapse CBF change (ΔCBF%) to track the dynamics of different vascular compartments (e.g., arterioles and venules) in response to cocaine (reprinted from [47]).

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