|
| Central nervous system (CNS) diseases studied with OCT | Study type (target) | Applications | References |
|
| Multiple sclerosis (MS) | Clinical (human retina) | Diagnostic biomarker development, measuring outcome of drug trials | [64, 65] |
|
| Optic neuritis (ON) | Clinical (human retina) | Diagnostic biomarker development, measuring outcome of drug trials | [17, 66, 67] |
|
| Parkinson’s disease (PD) | Clinical (human retina) | Diagnostic biomarker development, measuring disease severity | [26, 68] |
| Nonclinical (rodent brain) | Guiding deep brain stimulation therapy | [69] |
|
| Alzheimer’s disease (AD) | Clinical (human retina) | Diagnostic biomarker development | [26, 70] |
|
| Schizophrenia | Clinical (human retina) | Diagnostic biomarker development | [25, 71] |
|
| Optic nerve edema | Clinical (human retina) | Diagnostic biomarker development | [25] |
|
| Optic neuropathies (hereditary/toxic/nutritional) | Clinical (human retina) | Diagnostic biomarker development | [25] |
|
| Glaucoma | Clinical (human retina) | Diagnostic biomarker development, measuring outcome of drug trials | [25, 72] |
|
| Amblyopia | Clinical (human retina) | Studying retinal involvement | [25] |
|
| Neurosarcoidosis | Clinical (human retina) | Studying retinal involvement | [25] |
|
| Obstructive sleep apnea-hypopnea syndrome | Clinical (human retina) | Studying retinal involvement | [25] |
|
| Friedreich’s ataxia | Clinical (human retina) | Studying retinal involvement | [25] |
|
| Amyotrophic lateral sclerosis (ALS) | Clinical (human retina) | Diagnostic biomarker development | [73] |
|
| Gaucher disease | Clinical (human retina) | Diagnostic biomarker development | [74] |
|
| Bipolar disorder | Clinical (human retina, ganglion cell layer) | Diagnostic biomarker development | [75] |
|
| Sialidosis | Clinical (human retina) | Studying retinal involvement | [76] |
|
| Stroke (hemorrhagic/ischemic) | Nonclinical (rodent brain) | Studying stroke recovery | [3, 77–79] |
|
| Epilepsy | Clinical (human retina) | Studying drug resistance, studying retinal involvement | [80, 81] |
| Nonclinical (rodent brain) | Epilepsy mapping | [82] |
|
| Traumatic brain injury (TBI) | Nonclinical (rodent brain) | Studying TBI recovery | [3, 83, 84] |
|
| Brain tumor | Clinical (human brain, ex vivo human brain tissue) | Intraoperative neurosurgery guidance, diagnostic assessment | [5, 18, 85] |
| Nonclinical (rodent brain) | Intraoperative neurosurgery guidance | [18, 22, 86] |
|
| Usher syndrome | Clinical (human retina) | Studying retinal involvement | [87] |
|
| Huntington’s disease | Clinical (human retina) | Studying retinal involvement | [88] |
|
| Wilson’s disease | Clinical (human retina) | Studying retinal involvement | [89] |
|
| Migraine | Clinical (human retina) | Diagnostic biomarker development | [25] |
|
