Journal of Mycology / 2014 / Article / Tab 4

Research Article

Species Diversity, Antifungal Susceptibility, and Virulence Attributes of Candida Colonising the Oral Cavities of Adult Diabetic Patients

Table 4

Antifungal susceptibility pattern of the isolates.

SpeciesAmphotericin BKetoconazoleFluconazoleVoriconazole

C. albicans ()
 Diabetes: 26S-26S-26S-26S-26
R-0R-0R-0R-0
 Healthy: 18S-18S-18S-18S-18
R-0R-0R-0R-0
C. tropicalis ()
 Diabetes: 8S-8S-8S-8S-8
R-0R-0R-0R-0
 Healthy: 1S-1S-1S-1S-1
R-0R-0R-0R-0
C. krusei ()
 Diabetes: 7S-7S-7S-0S-7
R-0R-0R-7R-0
 Healthy: 0
C. parapsilosis ()
 Diabetes: 4S-4S-4S-4S-4
R-0R-0R-0R-0
 Healthy: 1S-1S-1S-1S-1
R-0R-0R-0R-0
C. glabrata ()
 Diabetes: 2S-2S-2S-1S-2
SDD-1
R-0R-0R-0R-0
 Healthy: 3S-3S-3S-3S-3
R-0R-0R-0R-0
C. magnoliae ()
 Diabetes: 1S-1S-1SDD-1S-1
R-0R-0R-0R-0
 Healthy: 0
C. kefyr ()
 Diabetes: 1S-1S-1S-1S-1
R-0R-0R-0R-0
 Healthy: 0
C. rugosa ()
 Diabetes: 1S-1S-1SDD-1S-1
R-0R-0R-0R-0
 Healthy: 0
Others
Trichosporon asahii ()
  Diabetes: 1S-1S-1SDD-1S-1
R-0R-0R-0R-0
  Healthy: 0

S: sensitive; R: resistant; SDD: susceptible dose dependent; Amphotericin B: sensitive (S) ≤ 0.5 g/mL, resistant (R) ≥ 1 g/mL; Fluconazole: sensitive (S) ≤ 8 g/mL, SDD 16–32 g/mL, resistant (R) ≥ 64 g/mL; Ketaconazole: resistant (R) ≥ 1 g/mL; Itraconazole (S) ≤ 0.125 g/mL, SDD 0.25–0.5, Resistant (R) ≥ 1 g/mL; Voriconazole (S) ≤ 1.