Cation Involvement in Telomestatin Binding to G-Quadruplex DNA
Figure 1
Chemical structure of telomestatin and folding pattern of the three G-quadruplexes studied here. adopts a parallel fold and can incorporate three ammonium ions between its four G-quartets [21], the 4-repeat telomeric sequence adopts an intramolecular antiparallel fold in ammonium acetate and incorporates up to two ammonium ions [22], and the Pu22myc promoter sequence adopts a predominantly parallel fold in ammonium acetate and incorporates two ammonium ions [23].
