Research Article

Synthesis of Macrocyclic Hexaoxazole (6OTD) Dimers, Containing Guanidine and Amine Functionalized Side Chains, and an Evaluation of Their Telomeric G4 Stabilizing Properties

Table 1

Δ 𝑇 𝑚 values by FRET melting assay.

G4 ligands23
Δ 𝑇 𝑚 at 1 𝜇 M G4 ligands ( Δ 𝑇 𝑚 / C )

Flu-telo211014
Flu-ds2600