“<i>One Ring to Bind Them All</i>”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles

<table class="table-group" width="800px"><tr class="fig-image" id="a"><td><img alt="460561.fig.003a" src="https://static.hindawi.com/articles/jna/volume-2010/460561/figures/460561.fig.003a.jpg"/></td></tr><tr class="fig-caption"><td align="center"><table><tr><td><b>(a) </b>Homodimeric macrocycles</td></tr></table></td></tr><tr class="fig-image" id="b"><td><img alt="460561.fig.003b" src="https://static.hindawi.com/articles/jna/volume-2010/460561/figures/460561.fig.003b.jpg"/></td></tr><tr class="fig-caption"><td align="center"><table><tr><td><b>(b) </b>Heterodimeric macrocycles</td></tr></table></td></tr><tr class="fig-image" id="c"><td><img alt="460561.fig.003c" src="https://static.hindawi.com/articles/jna/volume-2010/460561/figures/460561.fig.003c.jpg"/></td></tr><tr class="fig-caption"><td align="center"><table><tr><td><b>(c) </b>Homodimeric pendant-arm macrocycles</td></tr></table></td></tr><tr class="fig-image" id="d"><td><img alt="460561.fig.003d" src="https://static.hindawi.com/articles/jna/volume-2010/460561/figures/460561.fig.003d.jpg"/></td></tr><tr class="fig-caption"><td align="center"><table><tr><td><b>(d) </b>Homotrimeric macrocycles</td></tr></table></td></tr></table>

<table>Structures of the 26 studied CBIs; see text below for the explanations of the color codes related to affinity and selectivity of the ligands.</table>

Journal of Nucleic Acids

fig3

Figure 3

Figure 3: “<i>One Ring to Bind Them All</i>”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles 

Journal of Nucleic Acids

“One Ring to Bind Them All”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles

Figure 3