Is the Comet Assay a Sensitive Procedure for Detecting Genotoxicity?

Figure 1

Comet assay and Comet assay/araC in TK6 cells. Slides for Comet assay were prepared immediately after the exposure to chemical mutagens for 2 h with or without araC/HU, or 2 h culture with or without araC/HU after UVC irradiation. Electrophoresis was conducted at pH>13. Reproducibility was ascertained by three independent experiments, and representative data are shown. The error bars indicate standard errors of the mean. ^∗Significant difference from untreated control: 𝑃<.05.

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