Polymorphic Nucleic Acid Binding of Bioactive Isoquinoline Alkaloids and Their Role in Cancer

Table 5

Effect of berberine incubated with S180 cells in vitro^a.

Pathway	Percent control
	4 𝜇g/mL	40 𝜇g/mL
Glycine → [^14C] Protein	2.9	0.1
Thymine →[^3H] DNA	48.9	1.6
Uridine →[^3H] RNA	13.4	0

^aData obtained from W. A. Creasey [80].