Research Article

Evaluation of Human Telomeric G-Quadruplexes: The Influence of Overhanging Sequences on Quadruplex Stability and Folding

Table 1

Oligodeoxynucleotides and their sequences used in this study.

NameN. nt.Sequence 5 3

TEL1 21GGGTTAGGGTTAGGGTTAGGG
TEL1-TTA24GGGTTAGGGTTAGGGTTAGGGTTA
TEL245GGGTTAGGGTTAGGGTTAGGGTTAGGGTTAGGGTTA GGG TTAGGG
TEL1-5-T-728TTTTTTT-GGGTTAGGGTTAGGGTTAGGG
TEL1-3-T-728GGGTTAGGGTTAGGGTTAGGG-TTTTTTT
TEL1-5-A-728AAAAAAA- GGGTTAGGGTTAGGGTTAGGG
TEL1-3-A-728GGGTTAGGGTTAGGGTTAGGG-AAAAAAA
TEL1-5-T-1132TTTTTTTTTTT-GGGTTAGGGTTAGGGTTAGGG
TEL1-3-T-1132GGGTTAGGGTTAGGGTTAGGG-TTTTTTTTTTT
TEL1-3-TTA-1132GGGTTAGGGTTAGGGTTAGGG-TTATTATTATT
TEL1-5-TTA-1132TTATTATTATT GGGTTAGGGTTAGGGTTAGGG-
TEL1-3-5-T-735TTTTTTT-GGGTTAGGGTTAGGGTTAGGG-TTTTTTT
TEL1-3-T-1839GGGTTAGGGTTAGGGTTAGGG-TTTTTTTTTTTTTTTTTT
TEL1-5-T-1839TTTTTTTTTTTTTTTTTT-GGGTTAGGGTTAGGGTTAGGG
TEL1-3-5-A-739AAAAAAA- GGGTTAGGGTTAGGGTTAGGG-AAAAAAA
TEL1-5-TTA-1839TTATTATTATTATTATTA-GGGTTAGGGTTAGGGTTAGGG
TEL1-3-5-TTA-18 57TTATTATTATTATTATTA-GGGTTAGGGTTAGGGTTA GGG-TTATTATTATTATTATTA
TEL1-ran 39GATCCCAGATCTTC-GGGTTAGGGTTAGGGTTAGGG -CAGA