Table 1: E. coli proteins that interact with the 𝛽 clamp via the 𝛽 -binding pentapeptide motif QL[SD]LF or similar sequence [67].

𝛽 -interacting proteins 𝛽 -binding sequenceReferences

UmuD 1 4 T F P L F 1 8 [52, 53] ( 1 )
DNA Pol V (UmuC) 3 5 7 Q L N L F 3 6 1 [127, 128]
DNA Pol IV (DinB) 3 4 6 Q L V L G L 3 5 1 [68, 127, 129]
DNA Pol II (Pol B) 7 7 9 Q L G L F 7 8 3 [127]
DNA Pol III ( 𝛼 -subunit) 9 2 0 Q A D M F 9 2 4 [130]
𝛿 -subunit Clamp Loader 7 0 A M S L F 7 4 [131]
MutS 8 1 2 Q M S L L 8 1 6 [132]
Hda 6 Q L S L P L 1 1 [133]

( 1 ) Although these residues reside in an important region for interactions with the 𝛽 clamp, their identity is not required for UmuD to interact with 𝛽 (see text Section 5).