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Journal of Nucleic Acids
Volume 2010, Article ID 947859, 12 pages
http://dx.doi.org/10.4061/2010/947859
Review Article

Current Studies into the Genotoxic Effects of Nanomaterials

1Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 4 Medical Drive, Block MD10, Singapore 117597
2Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Block E5 no. 02-09, Singapore 117576

Received 24 May 2010; Revised 20 July 2010; Accepted 20 July 2010

Academic Editor: Shigenori Iwai

Copyright © 2010 Cheng-Teng Ng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Nanotechnology has created opportunities for engineers to manufacture superior and more efficient devices and products. Nanomaterials (NMs) are now widely used in consumer products as well as for research applications. However, while the lists of known toxic effects of nanomaterials and nanoparticles (NPs) continue to grow, there is still a vast gap in our knowledge about the genotoxicity of NMs. In this paper, we highlight some NMs of interest and discuss the current in vivo and in vitro studies into genotoxic effects of NMs.