Photoswitching of Site-Selective RNA Scission by Sequential Incorporation of Azobenzene and Acridine Residues in a DNA Oligomer
Figure 7
A proposed mechanism of the Photoswitching of site-selective RNA scission by azobenzene residues. (a) Azobenzene residues in trans form stack on the acridine in the adjacent residue and efficiently inhibit site-selective RNA activation. (b) When the solution is irradiated with UV light and the azobenzene isomerizes into cis isomer, the acridine is released from stacking and the cleavage reaction is significantly accelerated.
