Use of Specific Chemical Reagents for Detection of Modified Nucleotides in RNA
Figure 1
General chemical reactivity of nucleobases. Attack sites on the nucleobase are indicated by arrows. Open black arrows indicate oxidizing agents, filled black ones indicate alkylating electrophiles, and blue ones indicate nucleophiles. Numbering of the nucleobase atoms 1–6 for pyrimidines or 1–9 for purines is indicated outside the ring.
