Research Article

Influence of a Hairpin Loop on the Thermodynamic Stability of a DNA Oligomer

Figure 2

DSC thermograms and their model analysis: hairpin (HP) unfolding characterized in terms of a three-state model HP I S (a) and the corresponding fractions of species (b); duplex (D) unfolding characterized in terms of a two-state model D 2S (c) and the corresponding fractions of species (d). In panels (a) and (c) symbols represent experimental data points while lines of the same color correspond to the best-fit model functions ((14) and (18)).
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(a)
513910.fig.002b
(b)
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(c)
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(d)