Research Article

Influence of a Hairpin Loop on the Thermodynamic Stability of a DNA Oligomer

Table 2

Difference thermodynamic stability parametersa at 25°C exhibiting the influence of the TCTC loop to the unfolding features of the hairpin forming oligonucleotide (HP).

Transition

(HP → S)-(D → 2S)2.426.624.30.290.7
(I → S)-(D → 2S)−0.90.81.7−0.05−0.2

Error±3±3±3±0.07±0.3

aUnits: ( , ( ); for temperature dependence of , , and see Figure 4.