Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4
Figure 1
The effect of monovalent cations on Gq23 structure and thermal stability. (a) CD spectra at varying temperatures of Gq23 in a buffer containing 100 mM NaCl. (b) Gq23 melt at 292 nm in 100 mM NaCl. (c) Spectra of Gq23 in a buffer containing 100 mM KCl recorded at varying temperatures from 25°C to 75°C. (d) Gq23 melt at both 292 nm and 260 nm since both peaks were seen at both wavelengths throughout the temperature range.
