Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4
Figure 8
Effects of telomestatin and RPA on Gq23 in the presence of Na+ ions. (a) Chemical structure of telomestatin. (b) CD spectra of Gq23 at varying temperatures in the presence of a 1 : 5 molar ratio of Gq23 : telomestatin. (d) Spectra of increasing molar ratios of RPA (0–5) added to above Gq23 : telomestatin complex and (d) spectra of increasing molar ratios of RPA-CDE-core added to the Gq23 : telomestatin complex. All spectra were recorded in 100 mM NaCl.
