Branched RNA: A New Architecture for RNA Interference
Figure 1
Duplex RNA architectures for RNA interference. (a) Described previously in the introduction: (i) canonical siRNA antiparallel duplex; (ii) small internally segmented interfering RNA (sisiRNA); (iii) small hairpin RNA (shRNA); (iv) dumbbell siRNA. (b) Branched siRNA described in this study: (v) four-stranded RNA; (vi) two-stranded RNA.