Research Article

Identification of Genes Regulating Gene Targeting by a High-Throughput Screening Approach

Figure 6

Impact of EP300 and ATF7IP knockdown on the frequency of targeted integration at the endogenous RAG1 locus. (a) Experimental design. (b) Results. Mean stimulation of targeted integration events. The stimulation factor is expressed with respect to control siRNA (AS). Data were obtained from 4 and 3 independent experiments with EP300 siRNA and ATF7IP siRNA, respectively.
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(a)
947212.fig.006b
(b)