Research Article
Identification of Genes Regulating Gene Targeting by a High-Throughput Screening Approach
Table 2
Effect on gene targeting at the XPC4 locus of an siRNA targeting the ATF7IP gene.
| | siRNA | Number of G418R clones | Number of PCR+ clones | HGT (%) | Fold stimulation |
| Experiment 1 | AS | 120 | 5 | 4.2 | | ATF7IP | 146 | 15 | 10.3 | 2.4 | Experiment 2 | AS | 83 | 2 | 2.4 | | ATF7IP | 114 | 17 | 14.9 | 6.2 | Experiment 3 | AS | 73 | 1 | 1.3 | | ATF7IP | 58 | 6 | 10.3 | 7.9 |
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