Research Article

Features of “All LNA” Duplexes Showing a New Type of Nucleic Acid Geometry

Table 3

Overall helical parameters for natural (RNA and DNA) and modified nucleic acids (LNA, GNA, and PNA).

Base pairs/helical turnTwist (°)Rise (Å)P-P distance (Å)Pitch (Å)

RNA 11 32 2.6 6.0 30
DNA 10 36 3.4 7.0 34
LNA 14 26 2.8 5.6 39
GNA 16 22.9 3.8 5.4 60
PNA 18 19 3.2 5.4 58