Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside
The of the duplexes formed between modified (7X) or unmodified (7A) oligonucleotide and complementary 2′-O-methyl-RNA (or DNA) sequences bearing A, G, U (or T), or C nucleoside opposite to the artificial nucleoside 1 (in the case of oligonucleotide 7X) or adenosine (in the case of oligonucleotide 7A) in the presence and absence of Pd2+; [oligonucleotides] = 3.0 μM, [K2PdCl4] = 0/3.0 μM, I(NaClO4) = 0.1 M; pH = 7.4.
/°C, duplex with 7X
/°C, duplex with 7A
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.